Cactus Juice
Fights Cholesterol
Betalains May Limit Production of LDL Cholesterol in Humans
The juice from the Nopal cactus which grows in the Sonoran Desert is rich in Betalains one of which Betanin not only produces a red skin fruit but also inhibits the myeloperoxidase/nitrite-induced oxidation of human low-density lipoproteins according to a study by Allegra M, Tesoriere L, Livrea MA. of Department of Pharmaceutical, Toxicological and Biological Chemistry, Università di Palermo, Italy.
Production of nitrogen dioxide by the activity of myeloperoxidase (MPO) in the presence of nitrite is now considered a key step in the pathophysiology of low-density lipoprotein (LDL) oxidation. This study shows that Betanin, a phytochemical of the betalain class, inhibits the production of lipid hydroperoxides in human LDL submitted to a MPO/nitrite-induced oxidation. Kinetic measurements including time-course of particle oxidation and Betanin consumption, either in the presence or in the absence of nitrite, suggest that the antioxidant effect is possibly the result of various actions. Betanin scavenges the initiator radical nitrogen dioxide and can also act as a lipoperoxyl radical-scavenger. In addition, unidentified oxidation product(s) of Betanin by MPO/nitrite inhibit(s) the MPO/nitrite-induced LDL oxidation as effectively as the parent compound. In the light of Betanin bio availability and post-absorption distribution in humans, present findings may suggest favourable in vivo activity of this phytochemical
David Ogden
CEO TheInterbiz LLC
Independent TriVita Affiliate 13142173
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